Valter Longo, Ph.D.
Inventor of the Fasting Mimicking Diet
Dr. Longo is the Director of the Longevity Institute at University of Southern California and the inventor of the Fasting Mimicking Diet (FMD) nutritechnology. He is considered by many to be the global leader in nutrition and aging. Professor Longo discovered 20 years ago that two out of the three pathways caused cellular aging. His research team then embarked on a journey to uncover an impactful intervention that slows or reverses biological aging in order to delay the onset of age related chronic diseases. If you think about it, if Alzheimer’s disease, Diabetes type 2, most cancers, and most cardiovascular diseases appear at later age in life, it is because aging is the catalyst of these diseases, and therefore optimizing the way we age increases Healthspan, the healthy part of human life prior to disease onset.
Professor Longo then proved that periodic fasting, done for several consecutive days, is a very powerful intervention that our body learned to naturally cope with by protecting and rejuvenating itself, both anti-aging measures. Because it is difficult and risky nowadays to fast on water only, Professor Longo, under the sponsorship of the National Institute of Health, National Cancer Institute, and National Institute on Aging, has developed a natural plant based meal program named Fasting Mimicking Diet (FMD) which imitates fasting while feeding the body. Professor Longo’s work has been published in top scientific journals like Cell, Nature, Science, Journal of Translational Medicine, and covered by top global media like CNN, FOX, BBC, New York Times, Washington Post, etc.
Read scientific articles on the Fasting Mimicking Diet.
Clinical Study Methodology
Randomized controlled trial of 100 subjects, 71 completed 3 cycles of the ProLon® either in a randomized phase (N=39) or after being crossed over from a control diet group to the FMD group (N=32). Control subjects continued their normal diet. ProLon® participants consumed the fasting mimicking diet (FMD) for 5 consecutive days per month for 3 months. Measurements were performed prior to the diet (Before) and during the recovery period after the 3rd cycle (After).
Min Wei; Sebastian Brandhorst et al.
Fasting‐Mimicking Diet and Risk Factors for Aging, Diabetes, Cancer and Cardiovascular Disease.
Science Translational Medicine – February 15, 2017
Fasting Mimicking Diet Patents
Methods and diets for lowering glucose and/or IGF-1 levels
Patent Number: US9237761 B2
Publication Date: Jan 19, 2016
Inventors: Valter D. Longo, Sebastian Brandhorst, Morgan Elyse Levine
ABSTRACT
A method of improving longevity and/or alleviating a symptom of aging or preventing age related diseases is provided. The method includes a step in which the subject’s average and type of daily protein intake, IGF-I, and IGFBP1 levels, and risk factors for overall mortality, cancer and diabetes are determined. With respect to protein consumption, the relative amounts of protein calories from animal and plant sources are determined.